If you plan to have children, talk with your doctor before using this medicine. It is very important that your doctor check your or your child’s progress at regular visits to make sure that this medicine is working properly. Blood and urine tests may be needed to check for unwanted effects. Enter medications to view a detailed interaction report using our Drug Interaction Checker.
Dispensing and Administration Precautions
Peak pain intensity difference for all active‐treatment groups occurred between 2 and 3 hours postdose (Figure 4A). For the relief of the signs and symptoms of rheumatoid arthritis, the recommended starting and maintenance oral dose of meloxicam tablets is 7.5 mg once daily. Some patients may receive additional benefit by increasing the dose to 15 mg once daily. Use of NSAIDs, including meloxicam, at about 20 weeks gestation or later in pregnancy may cause fetal renal dysfunction leading to oligohydramnios and, in some cases, neonatal renal impairment.
How do the doses compare between meloxicam and Celebrex?
Consider potential benefits and risks of meloxicam therapy as well as alternative therapies before initiating therapy with the drug. Use lowest effective dosage and shortest duration of therapy consistent with the patient’s treatment goals. Both meloxicam and ibuprofen belong to the class of medicines known as nonsteroidal anti-inflammatory drugs (NSAIDs).
To view the complete list of warnings, precautions and side effects for meloxicam or Celebrex, review their individual product information, and talk to your healthcare provider to determine if either product might be an option for you. Most people can take NSAIDs on a short-term basis and at recommended doses without problems. But side effects can be difficult to predict in an individual patient and may come without warning, especially at high doses or when used over a long period of time.
- In contrast, ibuprofen is short-acting and is available over the counter (OTC) in some formulations.
- Discontinue meloxicam if oligohydramnios occurs and follow up according to clinical practice see Use in Specific Populations (8.1).
- But side effects can be difficult to predict in an individual patient and may come without warning, especially at high doses or when used over a long period of time.
Plasma Protein Binding
To date, this is the only study demonstrating a significant difference between the 30‐mg and 60‐mg doses of meloxicam IV. Summed pain intensity difference over 24 hours postdose, the primary efficacy variable, was the sum of the time‐weighted pain intensity difference scores measured as the intensity change from the baseline pain intensity score. An analysis of covariance model with treatment as a factor and baseline pain intensity as a covariate was used to analyze the time‐weighted summed pain intensity difference over 24 hours postdose. This model also was applied, as appropriate, to analyses of secondary end points including pain relief, time‐weighted sum of total pain relief, and global evaluation scores. Safety assessments performed during the 24‐hour postdose period included monitoring adverse events and vital signs (heart rate, systolic and diastolic blood pressure).
Related/similar drugs
Overall, meloxicam IV 60 mg produced the greatest reduction in pain, followed by meloxicam IV 30 mg and 15 mg. Highly significant differences in pain intensity were seen for active treatment groups vs placebo in every efficacy analysis. Moreover, statistically significant differences in the primary efficacy variable (time‐weighted summed pain intensity difference over 24 hours postdose) were noted for meloxicam IV vs placebo and for ibuprofen vs placebo.
- Oxaprozin, aspirin, ibuprofen, indomethacin, naproxen, and sulindac have comparable efficacy in the treatment of rheumatoid arthritis.
- This is not all the information you need to know about Celebrex or meloxicam for safe and effective use and does not take the place of your doctor’s directions.
- If you’re unsure of the right dose, it’s worth a call to your healthcare provider.
- Meloxicam tablets are indicated for relief of the signs and symptoms of pauciarticular or polyarticular course Juvenile Rheumatoid Arthritis in patients who weigh ≥60 kg see Dosage and Administration (2.4) and Clinical Studies (14.2).
The primary difference between these two similar medications is that meloxicam is a long-acting NSAID that is only available via prescription. In contrast, ibuprofen is short-acting and is available over the counter (OTC) in some formulations. Neither substance is considered particularly addictive, but like any medications, they can be abused. IV meloxicam not studied in patients with moderate or severe renal impairment; use not recommended. IV meloxicam contraindicated in patients with moderate to severe renal impairment who are at risk for renal failure because of hypovolemia.
Geriatric Patients
The American Society of Health-System Pharmacists, Inc. represents that the information provided in the accompanying monograph was formulated with a reasonable standard of care, and in conformity with professional standards in the field. The manufacturer’s labeling should be consulted for more detailed information. The American Society of Health-System Pharmacists, Inc. does not endorse or recommend the use of any drug.
Melixocam vs. Ibuprofen: Which is better for pain relief?
However, some studies have shown that they may be equally effective. The study protocol and written informed consent forms were reviewed and approved by an institutional review board (Aspire IRB, Santee, California) before study initiation. All subjects provided informed consent before completing any study activities. This was a single‐center, randomized, double‐blind, placebo‐ and active‐controlled, single‐dose study conducted in the United States in healthy adult men and women who planned to undergo surgical removal of impacted third molars. If you or a loved one are struggling with substance misuse with acetaminophen, opioids, ibuprofen, meloxicam, or any other prescription or OTC medication, practical help is available. Professional treatment can help you find relief from painkiller addiction while still pursuing practical solutions for dealing with acute or chronic pain.
Each medication has its place in the grand tapestry of pain management, meloxicam 15 mg compared to ibuprofen and knowing when to wield them can make all the difference. Remember, it’s all about taking care of yourself, one step at a time. Meloxicam and ibuprofen are both nonsteroidal anti-inflammatory drugs (NSAIDs).
Drugs Affecting Hepatic Microsomal Enzymes
You might be wondering, “How does 15 mg meloxicam equals how much ibuprofen?” Well, that’s a good question. This is not all the information you need to know about Celebrex or meloxicam for safe and effective use and does not take the place of your doctor’s directions. Review the full product information and discuss this information and any questions you have with your doctor or other health care provider. Do not use meloxicam or Celebrex if you have a history of asthma, urticaria (hives) or other allergic-type reactions (including anaphylaxis) after taking aspirin or other NSAIDs. Both medicines are approved to treat Rheumatoid arthritis, osteoarthritis and Juvenile Rheumatoid Arthritis (JRA), but Celebrex is approved for a few additional uses.
Each medication, like meloxicam and ibuprofen, has its own strengths and weaknesses. You want to make sure you’re making the best choice for your health, and that starts with a conversation. Meloxicam and Celebrex are both in the large class of drugs known as NSAIDs and share similar side effects such as stomach pain, nausea, diarrhea, heartburn, and gas (flatulence). Other side effects they share include headache, dizziness, edema (fluid retention), rash, sore throat, back pain and flu-like symptoms, among others. Oxaprozin, aspirin, ibuprofen, indomethacin, naproxen, and sulindac have comparable efficacy in the treatment of rheumatoid arthritis.
Always keep those lines of communication open with your healthcare provider, and you’ll be doing just fine. If your pain feels like it’s out of control or if you’re experiencing side effects from any medication, don’t wait. Maybe you tried 15 mg meloxicam for a while, but it’s just not cutting it. Or, perhaps you notice that your trusty ibuprofen isn’t working like it used to. Maybe it’s time for a team-up with a healthcare pro who can help you find the right balance.